Abstract

The polar lipid fraction E (PLFE) isolated from the thermoacidophilic archaeon Sulfolobus acidocaldarius contains exclusively bipolar tetraether lipids, which are able to form extraordinarily stable vesicular membranes against a number of chemical, physical, and mechanical stressors. PLFE liposomes have thus been considered appealing biomaterials holding great promise for biotechnology applications such as drug delivery and biosensing. Here we demonstrated that PLFE can also form free-standing “planar” membranes on micropores (∼100 μm) of polydimethylsiloxane (PDMS) thin films embedded in printed circuit board (PCB)-based fluidics. To build this device, two novel approaches were employed: (i) an S1813 sacrificial layer was used to facilitate the fabrication of the PDMS thin film, and (ii) oxygen plasma treatment was utilized to conveniently bond the PDMS thin film to the PCB board and the PDMS …

Date

2014

Authors

Xiang Ren, Kewei Liu, Qingwei Zhang, Hongseok “Moses” Noh, E Caglan Kumbur, Wenqiao Wayne Yuan, Jack G Zhou, Parkson Lee-Gau Chong

Journal

ACS applied materials & interfaces

Volume

6

Issue

15

Pages

12618-12628

Publisher

American Chemical Society