Through collaborations with government agencies, industry partners, and academic colleagues and students, ISI Centers and Labs cover a diverse range of disciplines. Utilizing rigorous design, modeling, and prototyping techniques, our broad capabilities facilitate the development of novel approaches to address issues in the natural and digital world.

ISI Centers and Labs are at the forefront of innovation, enabling trailblazing research to advance science, and usher in a more robust and secure technological age.

Analysis of Network Traffic (ANT) Lab

The ANT Lab is a research group spanning several departments at USC, and includes members from Colorado State University’s Computer Science Department and Los Alamos National Laboratory. The lab's goal is to improve the Internet by discovering new ways to understand network topology, traffic, security, use and abuse.

Visit ANT Website

Application Specific Intelligent Computing (ASIC) Lab

At the ASIC Lab, ISI scientists are working on changing the vision for computing. Researchers apply “alternate state variables,” such as electrons, photons, phonons, and magnetic spins, to deliver next-generation hardware fabrics for AI, smart sensors, smart and secure manufacturing, quantum information, and novel device integration.

Visit ASIC Website

Center on Knowledge Graphs (CKG)

ISI's Center on Knowledge Graphs research group combines artificial intelligence, the semantic web, and database integration techniques to solve complex information integration problems. The CKG group leverages general research techniques across information-intensive disciplines, including medical informatics, geospatial data integration and the social Web.

Visit CKG Website

CI Compass: An NSF Cyberinfrastructure Center of Excellence for Navigating the Major Facilities Data Lifecycle

CI Compass provides expertise and active support to cyberinfrastructure practitioners at NSF Major Facilities in order to accelerate the data lifecycle and ensure the integrity and effectiveness of the cyberinfrastructure upon which research and discovery depend.

Visit CI Compass Website

cyber DEfense Technology Experimental Research Laboratory (DeterLab)

ISI’s DeterLab emulates real-world complexity and scale necessary to evolve next generation solutions to help protect against sophisticated cyber attacks and network design vulnerabilities. The state-of-the-art scientific computing facility is a shared testbed providing a platform for research in cybersecurity and serving a broad user community, including academia, industry, and government.

Visit DeterLab Website

Laboratory for Quantum-Limited Information (QLIlab)

ISI’s new QLIlab is dedicated to understanding and demonstrating the fundamental physical limits for extracting information from physical signals using quantum mechanics. QLILab focuses on developing revolutionary designs for information processing systems that allow us to communicate and sense at the fundamental limits of nature, delivering capabilities in computing, communications, and sensing that are not possible using classical physics.

Visit QLIlab Website

USC-Lockheed Martin Quantum Computing Center (QCC)

A joint effort of Lockheed Martin Corporation and the University of Southern California, QCC is one of the world’s leading computer science and engineering research entities. Utilizing a D-Wave quantum annealing system for processing, applications include Big Data analysis, classification, optimization, and machine learning, helping support breakthroughs in aerospace, medical imaging, robotics, finance, web search, bioinformatics, and other disciplines.

Visit QCC Website

Science Automation Technologies (SciTech)

The SciTech research group aims to empower the scientific community by tightening the relations between the domain scientists and current computational resources. As a result, scientists can focus on their research questions, while the group's open-source tools provide the computational foundations to seamlessly run their experiments and analyses in local and distributed resources.

Visit SciTech Website

Space Engineering Research Center (SERC)

As a joint effort of the USC Viterbi School of Engineering and ISI, SERC combines disruptive space R&D, hands-on education of the second-generation workforce, and industry collaboration. The only "engineering teaching hospital" of its kind within the context of a diverse research university, SERC teaches students to build, test, and fly actual spacecraft and satellites, collaborating with government labs, industry and other USC schools and departments.

Visit SERC Website


Founded in 2012, the STEEL lab comprises members that conduct cutting-edge research in cybersecurity and testbed experimentation. The lab focuses on research in network-based cyber attacks, human aspects of cybersecurity, embedded cybersecurity, and binary analysis.

Visit STEEL Lab Website

Secure and Robust Electronics Center (SURE)

SURE seeks to meet an urgent cybersecurity need: electronics hardware safety. Dedicated to creating a US center of excellence for secure hardware R&D that helps protect national security, advance industry capabilities, and ensure citizens can rely on the integrity of their own devices, researchers at SURE utilize applied research to make chips trustworthy, secure, resilient, and reliable.

Visit SURE Website

Center for Vision, Image, Speech, and Text Analytics (VISTA)

VISTA combines ISI’s world-renowned expertise in machine-learning and deep-learning techniques to address pressing challenges in security, surveillance and multimedia content analysis. The center’s experienced academic and research staff push the boundaries of academic knowledge in areas spanning biometrics, face recognition, optical coherence tomography, speech, image processing, forensics, and multimedia.

Visit VISTA Website