Abstract

Purpose/Objective(s)
Initial breast intra-operative radiotherapy (IORT) results in clinical trials were encouraging though with longer follow up, increased local recurrences have been reported compared with whole breast radiation or other partial breast radiation including accelerated partial breast irradiation (APBI) methods. The goal of the study is to report our prospective single institution IORT breast study outcomes of local recurrence (LR) including true recurrence and breast elsewhere failures, breast cancer specific survival (BCSS), and overall survival (OS) with low energy x-ray IORT in early-stage breast cancer or ductal carcinoma in situ.
Materials/Methods
A total of 480 patients with early-stage breast cancer or DCIS were prospectively enrolled in an IRB approved single institution trial and treated with low energy X-ray IORT 20 Gy at time of breast-conserving surgery. Eligibility criteria included ≥ 45 years of …

Date

2023

Authors

A Suen, HT Pham, K Suen, S Narayanan, G Song, AB Post, P Mitsuyama, D Wechter, Q Le, J Grumley, N Robinson, M O'Malley, J Lavigne, L Stevens, V Youn, MS Yao

Journal

International Journal of Radiation Oncology, Biology, Physics

Volume

117

Issue

2

Pages

e209

Publisher

Elsevier