Publications

Test–retest repeatability of human speech biomarkers from static and real-time dynamic magnetic resonance imaging

Abstract

Static anatomical and real-time dynamic magnetic resonance imaging (RT-MRI) of the upper airway is a valuable method for studying speech production in research and clinical settings. The test–retest repeatability of quantitative imaging biomarkers is an important parameter, since it limits the effect sizes and intragroup differences that can be studied. Therefore, this study aims to present a framework for determining the test–retest repeatability of quantitative speech biomarkers from static MRI and RT-MRI, and apply the framework to healthy volunteers. Subjects (n= 8, 4 females, 4 males) are imaged in two scans on the same day, including static images and dynamic RT-MRI of speech tasks. The inter-study agreement is quantified using intraclass correlation coefficient (ICC) and mean within-subject standard deviation (σ e). Inter-study agreement is strong to very strong for static measures (ICC: min/median/max 0 …

Date
2017
Authors
Johannes Töger, Tanner Sorensen, Krishna Somandepalli, Asterios Toutios, Sajan Goud Lingala, Shrikanth Narayanan, Krishna Nayak
Journal
The Journal of the Acoustical Society of America
Volume
141
Issue
5
Pages
3323-3336
Publisher
AIP Publishing